Webb11 jan. 2013 · Leukocytes are able to use both routes in the brain endothelium as well [66,67], and the molecular mechanisms involved in the paracellular and transcellular migration pathways of leukocyte diapedesis have been intensively studied (reviewed in: [68,69]). Much less is known about the transmigration routes of tumor cells, especially in … Webb3 mars 2009 · The paracellular pathway is formed by tight junctions, located near the apical side of the cells, and the lateral intercellular spaces, where adjacent epithelial cells …

The Paracellular Pathway Elizabeth Purcell

Webb20 feb. 2008 · Leukocytes can transmigrate out of the vasculature by using either the paracellular or the transcellular route . The factors determining which pathway is … WebbThe paracellular pathway of transport is also important for the absorption of drugs in the gastrointestinal tract. It allows the permeation of hydrophilic molecules that are not able … sharing files in the cloud

paracellular pathway Encyclopedia.com

WebbIn epithelia, large amounts of water pass by transcellular and paracellular pathways, driven by the osmotic gradient built up by the movement of solutes. The transcellular pathway … WebbIntestinal permeability; Mucosal immunity; Psychological stress WebbThese cell-to-cell adhesion structures act as gatekeepers of the paracellular pathway (Figure 1b) by regulating the passive diffusion of molecules and ions into the brain [23,35,36]. The establishment of TJs at the BBB leads to a high electric resistance (>1000–3000 Ω cm 2 ) across the interface [ 37 , 38 ]. sharing files on a network windows 10