Imine hydroboration
WitrynaHydroboration of nitriles and imines mediated by main‐group metal Mg under solvent‐free conditions has been reported. Simple ethoxymagnesium chloride (EtOMgCl) was found to be an effective promoter of nitrile and imine hydroboration at room temperature. The selective reduction of nitriles over alkenes and alkynes and … Witryna7 wrz 2024 · Although there exists a variety of different catalysts for hydroboration of organic substrates such as aldehydes, ketones, imines, nitriles etc., recent evidence …
Imine hydroboration
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Witryna8 lis 2024 · The first use of diazaphospholenes as chiral catalysts has been demonstrated with enantioselective imine hydroboration. A chiral diazaphospholene prepared in a simple three-step synthesis from commercial materials has been shown to achieve the highest enantioselectivity for the hydroboration of alkyl imines with pinacolborane … Witryna3 kwi 2024 · The first catalytic inverse hydroboration of imines with N-heterocyclic carbene (NHC) boranes has been realized by means of cooperative organocatalysis and photocatalysis, providing a promising platform for promoting NHC-boryl radical chemistry under sustainable and radical-initiator-free conditions. The first catalytic inverse …
Witryna11 sty 2024 · Detailed DFT calculations and experiments were performed to study the hydroboration mechanisms of two different kinds of imines. Our results revealed that … Witryna28 paź 2024 · @article{Jaladi2024LithiumDH, title={Lithium diisobutyl-tert-butoxyaluminum hydride (LDBBA) catalyzed hydroboration of alkynes and imines with pinacolborane}, author={Ashok Kumar Jaladi and Hanbi Kim and Ji Hye Lee and Won Kyu Shin and Hyonseok Hwang and Duk Keun An}, journal={New Journal of …
Witryna11 sty 2024 · Boron Lewis acid-catalyzed and catalyst-free hydroboration reactions of imines are attractive due to the mild reaction conditions. In this work, the mechanistic details of the hydroboration reactions of two different kinds of imines with pinacolborane (HBpin) are investigated by combining density functional theory calculations and … Witryna17 wrz 2024 · Catalytic hydroboration of imines is a simple and straight-forward method for the preparation of amines, unlike conventional hydrogenation reactions and …
Witryna15 cze 2024 · A final comment on imine hydroboration is that in both cases 1 (73 % 0.5 h) offers marginally less reactivity than 3 (80 % 0.5 h). This difference may describe a subtle alkyl versus amido effect, whereby the replacement of one TMP anion for an i Bu anion imparts greater nucleophilicity onto the hydride, priming it for addition across the ...
Witryna27 mar 2024 · An overview of hydrogenation and hydroboration of amides is presented in the subsequent section. Finally, late-stage chemoselective functional group manipulation reduction is described, and we conclude the review with a summary of recent progress in catalytic metal-free reduction of amides. ... ester, ketone, … michelle thaller religionWitryna26 kwi 2024 · Consequently, catalytic hydroboration of a variety of imine substrates can be realized with 1 as the catalyst and HBpin as the terminal reagent. A mechanistic … michelle thaller personalWitryna27 lip 2024 · In summary, we have developed an approach for catalytic, mild and high-yielding hydroboration of nitriles. The catalyst system, consisting of a borane with comparably low Lewis acidity and a Lewis base, reacts with pinacolborane reversibly, providing a borenium cation for the imine activation while simultaneously generating a … the night hag visiting lapland witchesWitrynaThe β-diketiminato magnesium alkyl complex [LMgnBu] (L=CH{CMe(NDipp)} 2, Dipp=diisopropylphenyl) is shown to be a highly effective precatalyst for the … michelle tharpeWitryna1 wrz 2024 · LiAlH 4 catalysis: A combined experimental and theoretical investigation on LiAlH 4 catalyzed imine hydrogenation reveals mechanistic details as well as metal … the night has a thousand eyes karaokeWitrynaThe catalytic dehydrocoupling of amine–boranes has recently received a great deal of attention due to its potential in hydrogen storage applications. The use of aluminum catalysts for this transformation would provide an additional cost-effective and sustainable approach towards the hydrogen economy. Herein, we report the use of … michelle thanamichelle tharpe chicago