Cytohesin-1

WebJun 4, 2009 · Cytohesin-1 is up-regulated in human Mo-DCs during maturation, and is efficiently silenced by RNAi in both human and murine DCs. Western blot analysis shows that cytohesin-1 expression is up-regulated in human monocyte-derived dendritic cells (Mo-DCs) upon maturation induced by LPS (1 μg/mL)/TNF alpha (50 ng/mL; panel A lanes … WebWe next observed that both guanine nucleotide exchange factors, Cytohesin-1/2/3 (CYTH1/2/3, CYTHs) and ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1), interacted with Arf1. Inhibiting CYTHs or ARFGAP1 showed that Gln supplement or depletion activated or inactivated Arf1 through CYTHs or ARFGAP1, respectively. …

Recombinant Anti-Cytohesin 1 antibody [EPR10050] (ab154847)

WebCytohesin-2 is enriched in the perisynapse on the postsynaptic membrane of dorsal horn neurons and forms a protein complex with mGluR5 in the spinal cord. Central nervous system-specific cytohesin-2 conditional knockout mice exhibited reduced mechanical allodynia in inflammatory and neuropathic pain models. WebMay 3, 2024 · The cytohesin proteins, consisting of four closely related members (cytohesins-1, -2, -3, and -4), are a subfamily of the Sec7 domain-containing guanine nucleotide exchange factors for ADP... flink oracle connector https://iihomeinspections.com

Understanding the role of integrins in breast cancer …

WebJun 6, 2000 · Cytohesin-1 comprises an N-terminal coiled-coil domain, which may aid in oligomerization, a central Sec7 domain and a C-terminal module including the pleckstrin homology (PH) domain and a polybasic region. Cytohesin-1 specifically binds to the intracellular domain of the β-2 integrin chain and has been implicated in the functional … WebTDR Targets ID: 578688 Echinococcus granulosus, cytohesin 1 Source Database / ID: GeneDB pI: 8.4469 Length (AA): 449 MW (Da): 50086 Paralog Number: 0 flink oracle sink

Cytohesin 1 regulates homing and engraftment of human …

Category:ARF family G proteins and their regulators: roles in membrane ... - Nature

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Cytohesin-1

TDR Targets

WebApr 14, 2015 · The cytohesins are a class of BFA-resistant small GEFs for ADP-ribosylation factors (ARFs), which regulate cytoskeletal organization, integrin activation, or integrin signaling. The application of SecinH3 in human liver cells showed that insulin receptor complex-associated cytohesins are required for insulin signaling. Webfindings suggest that cytohesin-1 is a key regulator of neutrophil adhesion to endothelial cells and to components of extracellular matrix, which may influence cell emigration …

Cytohesin-1

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WebJul 7, 1998 · Cytohesin-1 (B2–1) is a guanine nucleotide exchange factor for human ADP ribosylation factor (Arf) GTPases, which are important for vesicular protein trafficking and … WebMar 11, 2014 · These data suggested that inhibiting cytohesins or ARNO as cytoplasmic activators of EGFR and IGF-I in colorectal cancer resulted in anti-proliferation, reduced invasion, decreased migration, and suppressed growth in vivo and in vitro. Therefore, cytohesins or ARNO may be a potential therapy target for some colorectal cancer. …

WebMar 21, 2024 · CYTH1 (Cytohesin 1) is a Protein Coding gene. Diseases associated with CYTH1 include Intellectual Developmental Disorder With Short Stature And Behavioral … WebOrthologs 1; Homo sapiens (human): CYTH1 (cytohesin 1) HGNC: EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Treefam: Mus musculus (house mouse): Cyth1 (cytohesin 1) Transitive Ortholog Pipeline: Transitive Ortholog Pipeline: Chinchilla lanigera (long-tailed chinchilla): Cyth1 (cytohesin 1) Transitive Ortholog Pipeline: …

Web丁香通为您提供PhosphoZyxin商品详情介绍：价格：询价，货号：8467，品牌：Cell Signaling Technology，产地：USA，详见丁香通PhosphoZyxin商品详情页； WebAll lanes : Anti-Cytohesin 1 antibody [EPR10050] (ab154847) at 1/1000 dilution Lane 1 : Raji cell lysate Lane 2 : Jurkat cell lysate Lane 3 : HuT-78 cell lysate Lysates/proteins at 10 µg per lane. Predicted band size: 46 kDa.

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WebFeb 23, 2024 · Adhesion is a key component of hematopoietic stem cell regulation mediating homing and retention to the niche in the bone marrow. Here, using an RNA interference … greater heights craneWebAug 18, 2003 · Cytoplasmic exchange factors for ARFs have been identified; they are called cytohesin-1 , ARNO (cytohesin-2) and GRP-1 (cytohesin-3) . Cytohesin-1 is a 47 … flink oracle mysqlWebJul 7, 1998 · Cytohesin-1 (B2–1) is a guanine nucleotide exchange factor for human ADP ribosylation factor (Arf) GTPases, which are important for vesicular protein trafficking and coatamer assembly in the cell. Cytohesin-1 also has been reported to promote cellular adhesion via binding to the β2 integrin cytoplasmic domain. greater heights crossfitWebNischarin is an intracellular tumor suppressor protein that interacts with the cytoplasmic domain of α5-integrin, discovered by us [ 49 ]. Overexpression of Nischarin blocks cell migration.... greater heights democratic clubWebCytohesin proteins are ubiquitous and have been implicated in several functions including cell spreading and adhesion, chemotaxis, protein trafficking, and cytoskeletal … greater heights definitionWebCYTIP cytohesin 1 interacting protein [ (human)] Gene ID: 9595, updated on 29-Mar-2024 Summary The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. greater heights counselingWebJan 8, 2024 · Cytohesin 1 is a β2 IBP, and particularly it interacts with the leukocyte integrin αLβ2. Cytohesin-1 function as a guanine-nucleotide exchange factor for some GTPases. flink oracle sql