Cancer/testis antigen family 45 member a10
WebMay 15, 2013 · Active antigen-specific immunotherapy may provide a valid therapeutic option for patients with NMIBC. Cancer-testis antigens (CTA) expressed in various tumour types and in a limited range of healthy tissues may represent potential targets for specific immunotherapy. MAGE-A10 is probably the most immunogenic antigen of the MAGE-A … WebMay 27, 2015 · Cancer/testis antigen family 45 member A8 Imported. Alternative names. Cancer/testis antigen 45A8 Curated. Gene names. Name. CT45A8 Imported. Organism names. Organism. Homo sapiens (Human) Taxonomic …
Cancer/testis antigen family 45 member a10
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WebMelanoma-associated antigen 3. MAGE-A3 is a cancer testis antigen that is expressed in approximately 30% of NSCLCs, as well as other malignancies, but not expressed in … WebCancer/Testis Antigen Family 45 Member A10: Protein Coding: 25: GC0XM135881: 15.90: 2: CT45A1: Cancer/Testis Antigen Family 45 Member A1: Protein Coding: 34: …
WebMar 6, 2024 · Cancer/testis antigens (CTAs) are reproductive tissue-restricted genes, frequently ectopic expressed in tumors. CTA genes associate with a poor prognosis in some solid tumors, due to their potential roles in the tumorigenesis and progression. However, whether CTAs relate with hepatocellular carcinoma (HCC) remains unclear. In this study, … Web300789 - CANCER/TESTIS ANTIGEN FAMILY 47, MEMBER A10; CT47A10 - CT47.10 - CT47A10 Toggle navigation . About ; Statistics . Update List ; Entry Statistics ; …
WebApr 27, 2024 · Lung cancer is the leading type of malignant tumour among cancer-caused death worldwide, and the 5-year survival rate of lung cancer patients is only 18%. Various oncogenes are abnormally overexpressed in lung cancer, including cancer/testis antigens (CTAs), which are restrictively expressed in the male testis but are hardly expressed in … WebGwendolyn K. Binder, Rafael G. Amado, in Second Generation Cell and Gene-based Therapies, 2024 The MAGE-A3 Experiences. Another cancer testis antigen with excellent expression across multiple tumours is MAGE-A3. MAGE is a large family of proteins, many of which have shared homology. Many MAGE family members have tumour-specific …
WebMar 15, 2024 · Cancer/testis (CT) antigens match these criteria for an ideal target, as CT antigens are tumor antigens that are identified with a normal expression and restricted to testicular, ovarian, fetal, and placental germ cells [4,5], but may also be detected in malignancies [6,7]. CT antigens are normally located in an immune-privileged site due to ...
WebNov 1, 2024 · Cancer/testis antigens (CTAs) are a class of tumor-associated antigens. Their high immunogenicity and tissue-specific expression shed light on their roles in cancer detection and treatment. As listed in the CTdatabase, the human genome encodes more than 200 CTA genes from 44 gene families [1]. It is speculated that CTA genes were … can people wear dog collarsWebNov 10, 2024 · Cancer testis antigens (CTAs) form a large family of proteins with highly restricted expression that is limited to male germ cells in the testis and trophoblast cells in the placenta. They are often re-expressed in tumors as a result of differential DNA methylation of their promoter regions, making them highly tumor-specific antigens. can people watch your smart tvWebCancer/testis antigens (CTAs) are a group of tumor antigens expressed in numerous cancer tissues, as well as in the testis and placental tissues. There are over 200 CTAs supported by serology and expression data. The expression patterns of CTAs reflect the similarities between the processes of gametogenesis and tumorigenesis. can people watch you through your phoneWebDescribed herein are compounds and compositions characterized, in certain embodiments, by conjugation of various groups, such as lipophilic groups, to an amino or amide group of a flame off canadaWebNX_P0DMU9 - CT45A10 - Cancer/testis antigen family 45 member A10 - Interactions. Unknown function flame of fell godWebGwendolyn K. Binder, Rafael G. Amado, in Second Generation Cell and Gene-based Therapies, 2024 The MAGE-A3 Experiences. Another cancer testis antigen with … flame off fire retardantWebIt is clearly showed that MAGE-A10 is frequently expressed in the group of TN patients, where the majority (85.7%) of tumors express this CTA, representing a potentially highly attractive target of active specific immunotherapies. Recent studies indicate that ER/PR/HER-2-negative (triple-negative, TN) breast cancers may be “CTA-rich” tumors, … flame officer ffxiv